Observational study of how the brain processes sound in Rett syndrome

You may qualify if

• Rett Syndrome Participants:
• Have a clinical diagnosis of classic Rett syndrome
• Have a pathogenic MECP2 genetic variant confirmed via genetic testing
• Are past the clinical regression stage
• Are within the eligible age range for the study (2 years or older)
• Are able to tolerate the noninvasive EEG recording
• Parent or caregiver is willing and able to provide parental permission and complete questionnaires and interviews
• Neurologically healthy individuals ages 2 years or older
• Are able to tolerate the noninvasive EEG recording

You can't join if

• Experiences hearing impairment or hearing loss
• Presence of medical conditions that would prevent safe participation in EEG recording
• Inability to tolerate EEG procedures
• Any condition that in the opinion of the investigator would interfere with study participation or data quality Controls
• Experiences hearing impairment or hearing loss
• Medical history of genetic, neurological, or psychiatric disorders
• History of special education services
• Inability to tolerate EEG procedures
• Any condition that in the opinion of the investigator would interfere with study participation or data quality