agenT-797 with standard care for severe pneumonia with moderate to severe breathing failure

You may qualify if

• Admission to an intensive care unit (ICU) with severe pneumonia of any etiology (viral, bacterial, fungal, or mixed), with and without trauma based on clinical suspicion
• Acute hypoxemic respiratory failure (AHRF)
• Evidence of moderate to severe acute respiratory distress syndrome (ARDS) based on Global ARDS criteria
• Onset of severe pneumonia with AHRF ≤7 days prior to informed consent

You can't join if

• More than two vasopressors to maintain a mean arterial pressure ≥65 millimeters of mercury at the time of informed consent
• Pregnancy or breastfeeding
• History of cytokine release syndrome, as documented in the medical record or reported by the participant, legally authorized representative, or close relative
• Current participation in another interventional clinical trial, or receipt of an investigational medicinal product within 30 days prior to screening, unless reviewed and approved in writing by the medical monitor