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AutismNutrition and dietBehavioralChildren's healthBehavioral

What this study is

Obesity is one of the most common health conditions among autistic young people and its prevalence rises at faster rates for autistic-relative to non-autistic-individuals. This places them at heightened risk for cardiovascular disease (CVD) and mortality before they enter adulthood. Studies have identified three key contributing factors to CVD outcomes in autistic individuals: unhealthy lifestyle behaviors, Adverse Childhood Experiences (ACEs), and chronic stress.

This study will explore the effectiveness of two CVD-focused primary care interventions for autistic individuals (ages 9-26): (1) lifestyle medicine consultations tailored towards supporting health-promoting behaviors; and (2) a Cognitive Behavioral Therapy (CBT) intervention tailored towards addressing chronic stress that contributes to excess weight and maladaptive eating behaviors and results in obesity and CVD. Participants and their caregivers will be randomly placed into either the Lifestyle Medicine Group, CBT Group, or combined Lifestyle Medicine with CBT Group. Participants will respond to questionnaires and surveys measuring lifestyle habits, stress, and psychological risk factors at their first visit, 6-month visit, and 3 months post-intervention visit. Over the course of 6 months, participants will attend virtual sessions (up to three times a month) in accordance with their intervention group.

What's being tested

  • Lifestyle Medicine

    Intervention · BEHAVIORAL

    The intervention is a series of lifestyle medicine consultations.

  • Cognitive Behavioral Therapy (CBT)

    Intervention · BEHAVIORAL

    The intervention is a series of CBT sessions.

  • Lifestyle Medicine with CBT Group

    Intervention · BEHAVIORAL

    Receives both Lifestyle Medicine and CBT interventions

Study details

Official title
Autism Research Consortium on Physical Health: A Two-Part Intervention to Target Cardiovascular Health
Sponsor
University of California, Los Angeles
Conditions
Autism · Adverse Childhood Experience · Stress · Cardiovascular (CV) Risk
Enrolling
130 people
Starts
2026-08-05
Est. completion
2028-08-31
Design
Open-label, randomized, parallel groups
Record
View on ClinicalTrials.gov ↗