A new drug (HMPL-A830) for advanced solid tumors that progressed after standard treatment

You may qualify if

• Understood this study and are able to voluntarily sign the informed consent form (ICF);
• Male or Female, Age ≥ 18 years;
• Histological confirmed, unresectable, advanced or metastatic solid tumor
• Participants must have at least one measurable lesion per Response Evaluation Criteria in Solid Tumors(RECIST) v1.1
• Life expectancy ≥ 12 weeks
• Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0-1

You can't join if

• Use strong inhibitors of cytochrome P450 3A4 enzyme (CYP3A4), and inhibitors of P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) within 5 elimination half-lives or 2 weeks (whichever is longer) before the first dose of study drug
• Major surgery within 28 days prior to the first dose of study drug
• Active infection requiring systemic treatment
• History of inflammatory gastrointestinal diseases
• Known hypersensitivity to any component of HMPL-A830
• Pregnant (positive pregnancy test) or lactating;