What this study is
This randomized clinical trial is evaluating the impact of a structured peer support intervention (STEPP) on psychological distress and quality of life among patients undergoing hematopoietic stem cell transplantation.
What's being tested
- STEPP
Intervention · BEHAVIORAL
STEPP, a phone-delivered structured peer support intervention for patients preparing to undergo hematopoietic stem cell transplantation (HSCT), consists of five sessions which integrates evidence-based strategies from cognitive-behavioral therapy, mindfulness, and positive psychology with informational, emotional, and practical support. STEPP is manualized and delivered by an HSCT survivor who is trained and supervised by a clinical psychologist.
- Minimally Enhanced Usual Care Control
Intervention · OTHER
The minimally enhanced usual care control condition entail standard psychosocial care provided by social work and a comprehensive list of peer support resources available through participants academic hematopoietic stem cell transplantation centers and national organizations.
Study details
- Sponsor
- Brigham and Women's Hospital
- Conditions
- Hematopoietic Stem Cell Transplantation
- Enrolling
- 350 people
- Starts
- 2026-12-01
- Est. completion
- 2030-07-31
- Design
- Open-label, randomized, parallel groups
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 18 Years and overSex ALLHealthy volunteers Not acceptedYou may qualify if
- Adult patients (aged 18 years and older) with hematologic malignancies, scheduled to undergo autologous or allogeneic HSCT
- Ability to speak, read, and respond to questions in English or Spanish to complete study procedures
You can't join if
- Patients undergoing HSCT for benign hematologic conditions
- Patients with acute or unstable psychiatric or cognitive conditions (e.g., dementia) which the treating clinicians believe prohibits informed consent or compliance with study procedures
- Patients undergoing HSCT for the second time
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (3)
3 openDana-Farber Cancer Institute
Boston, Massachusetts, United States
- Hermioni Amonoo, MD, MPP, MPH · ContactHermioni_Amonoo@dfci.harvard.edu
Fred Hutchinson Cancer Center
Seattle, Washington, United States
- Stephanie J Lee, MD, MPH · Contactsjlee@fredhutch.org
Study team
Sponsor
Brigham and Women's Hospital
Study ID 26-274
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.