What this study is
The goal of this observational study is to understand how cancer makes children feel over time. The main things the researchers hope to learn are:
- When and how often do children have different feelings or sickness;
- Why do these feelings happen; and,
- How these feelings change a child's overall health.
Participants will answer simple surveys about their health.
What's being tested
- Health surveys
Intervention · OTHER
Participants will complete several surveys about their quality of life and health.
Study details
- Official title
- Defining Symptom Trajectories to Inform Risk-Stratified Approaches to Symptom Management in Children With Advanced Cancer
- Sponsor
- University of Wisconsin, Madison
- Conditions
- Advanced Cancer · Metastatic Disease · Cancer Treatment · Progressive Disease · Recurrent Cancer
- Enrolling
- 228 people
- Starts
- 2026-12-01
- Est. completion
- 2031-05-31
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 8 Years – 18 YearsSex ALLHealthy volunteers Not acceptedChildren
You may qualify if
- Aged 8-18 years
- Diagnosis of advanced cancer of any type made by the hematology, oncology, or cellular therapy team
- Undergoing cancer treatment or comfort care
- Be English or Spanish literate
You can't join if
- Any condition that would prevent participants from completing surveys
Caregivers
You may qualify if
- Aged >18
- Caregiver of a child diagnosed with advanced cancer
- English or Spanish literate
- Identified as being substantially involved in caring for the child
You can't join if
- Any condition that would prevent participants from completing surveys
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (5)
5 openChildren's Hospital Los Angeles
Los Angeles, California, United States
New York -Presbyterian Morgan Stanley Children's Hospital
New York, New York, United States
Nationwide Children's Hospital
Columbus, Ohio, United States
OHSU Doernbecher Children's Hospital
Portland, Oregon, United States
American Family Children's Hospital
Madison, Wisconsin, United States
Study team
Sponsor
University of Wisconsin, Madison
Study ID 2026-0259
Principal investigator
Kathleen (Kitty) Montgomery, PhD, RN, PCNS-BC
University of Wisconsin, Madison
Principal investigator
Kristine Kwekkeboom, PhD, RN, FAAN
University of Wisconsin, Madison
Principal investigator
Roger Brown, PhD
University of Wisconsin, Madison
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.