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Cerebellar StrokeBrain and nervesDevice

What this study is

The work will examine the mechanisms and potential therapeutic effects of transcranial magnetic stimulation on upper-limb sensorimotor function in individuals with cerebellar dysfunction, including those with damage due to stroke or autoimmune disease.

The study team will work toward a goal of non-invasive stimulation-based neuromodulatory interventions for cerebellar disorders using a closely integrated, clinically oriented cross-species approach. There will be a related study in nonhuman primates.

What's being tested

  • Transcranial Magnetic Stimulation

    Intervention · DEVICE

    Stimulation of continuous theta burst stimulation at 80% of resting motor threshold over the region targeted for modulation after behavioral testing, with resting of behavior afterwards.

Study details

Official title
Neuromodulation of Cerebellar Circuitry
Sponsor
George Wittenberg
Conditions
Cerebellar Stroke · Autoimmune Cerebellar Disorders
Enrolling
60 people
Starts
2026-12
Est. completion
2028-12
Design
Single-blind, randomized, single group
Record
View on ClinicalTrials.gov ↗