What this study is
In this research study, the investigators want to learn about new ways to use MRI (Magnetic Resonance Imaging) to take clearer pictures of the lungs. The investigators will be using types of MRI called UTE (Ultra Short Echo Time) and bSSFP (balanced Steady-State Free Precession) as well as traditional MRI. The investigators also want to collect images and health information about lungs that are healthy or those in people with different kinds of lung, muscular, and bone diseases. This collection will help us in the future to better understand lung variations in health and disease.
What's being tested
- MRI
Intervention · DIAGNOSTIC TEST
This intervention uses specialized MRI sequences, UTE and bSSFP, alongside traditional MRI to capture high-resolution images of lung structure and function. These sequences are optimized for imaging pulmonary tissues and airspaces, which is not typical in standard clinical MRI protocols. The study focuses on both healthy participants and those with lung, muscular, and bone diseases to evaluate variations in lung imaging.
Study details
- Official title
- Ultra-Short Echo Time 1H MRI in Individuals With Thoracic Musculoskeletal Disorders
- Sponsor
- Laura Walkup
- Conditions
- Muskuloskeletal Diseases · Healthy · Respiratory
- Enrolling
- 100 people
- Starts
- 2025-06-17
- Est. completion
- 2030-06
- Record
- View on ClinicalTrials.gov ↗
Who can join
Age 5 Years and overSex ALLHealthy volunteers AcceptedYou may qualify if
- Age ≥ 5 years
You can't join if
- History of any comorbidity reviewed at the Screening phone call that, in the opinion of the investigator, might confound the results of the study or pose an additional risk to the subject.
- Standard MRI exclusion criteria as set forth by the CCHMC Radiology Department and IRC.
- Pregnancy
Sign in and we'll check these against your records.Full criteria on ClinicalTrials.gov ↗
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Study locations (1)
1 openCincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
- Ashley Borden, MPH · Contact5136360143ashley.borden@cchmc.org
Recruiting
Study team
Sponsor
Laura Walkup
Study ID 2024-0256
Principal investigator
Laura Walkup, PhD
Children's Hospital Medical Center, Cincinnati
Frequently asked questions
The sponsor hasn't published answers to common questions for this trial.