A drug (DSP-2342) and its effects on brain chemistry and activity in schizophrenia

You may qualify if

• Right-handed, participants with schizophrenia between the ages of 18-50 years.

You can't join if

• Current substance misuse
• Pregnancy or breast feeding
• Subjects with electrocardiographic abnormalities (particularly QTc prolongation)
• Subjects with renal impairment
• Subjects with hepatic impairment
• Past or current neurological disorder (including stroke, brain tumor, epilepsy, Alzheimer's, Parkinson's or Huntington's disease)
• Non-schizophrenia cause of cognitive impairment
• Uncontrolled medical disorder that may interfere with cognition or compromise safety
• Head trauma with loss of consciousness in the last year or any evidence of functional impairment due to and persisting after head trauma
• Having a contraindication to MRI, including a pacemaker, defibrillator or other medical implant, other metal objects, or claustrophobia, or for having braces or other metal in the head region (likely to create an artifact on the MRI scans).
• Significant suicidal ideation
• Recent history of electroconvulsive therapy
• Medication changes in the past six weeks