Observational study of daily variation in anti-factor Xa levels in hospitalized trauma patients on blood thinners

You may qualify if

• Inpatient admission for acute traumatic injury ≥72 hours
• Prescribed LMWH subcutaneous for VTE chemoprophylaxis

You can't join if

• Pregnancy
• Brain hemorrhage or non-survivable injury
• Chronic Kidney disease ≥ 3b estimated Glomerular Filtration Rate (eGFR) less than 30 interferes with coagulation
• Chronic liver failure •-Acute stimulant use of cocaine and methamphetamine
• Active VTE or ongoing anticoagulation at admission
• History of coagulopathy or inherited bleeding disorders
• Chronic alcohol as defined as a documented diagnosis of alcohol use disorder or alcohol consumption exceeding established risk thresholds (men >14 drinks/week; women >7 drinks/week) within the prior 3-6 months
• Unmanaged psychiatric conditions as defined as diagnosed psychiatric disorder with evidence of inadequate or no active treatment or documented poor symptom control
• Neurologic injury involving hypothalamic or circadian regulatory centers