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PancreatitisAddictionMental healthBehavioralDrugPhase 4

What this study is

This study will look at how safe and how effective varenicline, a commonly used medication for smoking cessation, is in helping patients with pancreatitis stop smoking cigarettes. Individuals who agree to be part of the study will be treated with varenicline for 12 weeks, after which the investigators will see how many have stopped smoking.

What's being tested

  • Varenicline (VAR)

    Intervention · DRUG

    Varenicline is the treatment being offered in this treatment. Treatment will entail oral varenicline 1 mg twice a day (BID) for a total of 12 weeks. Initial titration begins in the following manner: * Days 1-3: 0.5 mg once daily * Days 4-7: 0.5 mg twice daily * Day 8 through end of treatment (12 weeks): 1 mg twice daily

Study details

Official title
Varenicline for Smoking Cessation in Pancreatitis: An Open-Label Trial
Sponsor
Mayo Clinic
Conditions
Pancreatitis · Chronic Pancreatitis · Acute Pancreatitis (AP) · Recurrent Acute Pancreatitis
Enrolling
45 people
Starts
2026-11-13
Est. completion
2029-11-01
Design
Open-label, single group, Phase 4
Record
View on ClinicalTrials.gov ↗