An imaging scan (68Ga-FAPI PET/MRI) to see how breast cancer responds to chemotherapy

You may qualify if

• Age ≥ 18
• ECOG Performance Status of ≤ 2
• Ability to review and signed informed consent
• Histologically confirmed, newly diagnosed invasive breast cancer
• Lymph node metastases (either histologically confirmed or radiographic evidence of lymph node metastases).
• Planned to undergo SOC NAC prior to surgical resection as outlined in section 4.1

You can't join if

• Pregnancy or lactation.
• Patients who cannot undergo PET/MRI scanning because of:; devices or implants that are not MRI safe; hypersensitivity or known allergy to gadolinium-based contrast agents; physical fitness not allowing scanning in prone for 30 minutes; weight limits (450 lb. weight limit)
• Severe kidney disfunction (estimated GFR < 30 ml/min/1.73 m2) (CKD-EPI (2021))
• Imaging features suspicious for concomitant in-situ cancer (LCIS/DCIS), such as nonbiopsied groups of microcalcifications
• Distant metastases (contraindication for NAC)