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HyperparathyroidismDiagnostics and screeningDrugEarly Phase 1

What this study is

Simplified from ClinicalTrials.gov

Testing a scan using a radioactive tracer (Flurpiridaz F-18 PET/CT) to find overactive parathyroid glands, small neck glands that control calcium, in adults 18 and older with primary hyperparathyroidism who have known or suspected parathyroid adenomas and are going to have surgery to explore several parathyroid glands. The study compares it with the standard sestamibi SPECT/CT scan.

Read the original summary from ClinicalTrials.gov

Study of Flurpiridaz F-18 PET/CT as a diagnostic imaging tool to detect abnormal parathyroid glands in patients with primary hyperparathyroidism, prior to multi-parathyroid gland surgical exploration. Patients with known or suspected parathyroid adenomas will be eligible for this study. Comparisons of diagnostic performance using Flurpiridaz F-18 PET/CT versus standard of care dual time point sestamibi SPECT/CT imaging will be tested.

What's being tested

  • Flurpiridaz PET/CT

    Intervention · DRUG

    Flurpiridaz is a FDA approved radiopharmaceutical used with PET/CT imaging

Study details

Official title
Flurpiridaz F-18 PET/CT Imaging for Detecting Parathyroid Adenomas in Patients With Primary Hyperparathyroidism
Sponsor
University of Pennsylvania
Conditions
Hyperparathyroidism
Enrolling
20 people
Starts
2026-08-15
Est. completion
2029-09-01
Design
Open-label, single group, Early Phase 1
Record
View on ClinicalTrials.gov ↗