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Neurotrophic KeratopathyGeneticsRare diseaseGeneticPhase 1, Phase 2

What this study is

Simplified from ClinicalTrials.gov

Testing a single-dose treatment (MR-146) to learn about its safety and the best dose for neurotrophic keratopathy, a disease of the cornea (the clear front of the eye), in adults 18 or older with stage 1 or 2 of it. Only people with stage 2 can join the study's second part.

Read the original summary from ClinicalTrials.gov

The objective of this study is to evaluate the safety, tolerability, and biologically effective dose (BED) of MR-146 for the treatment of Stage 1 and Stage 2 Neurotrophic Keratopathy (NK)

What's being tested

  • MR-146

    Intervention · GENETIC

    gene therapy product for the treatment of stage I/II NK.

Study details

Sponsor
Viatris Inc.
Conditions
Neurotrophic Keratopathy
Enrolling
18 people
Starts
2026-11
Est. completion
2028-11
Design
Open-label, non-randomized, single group, Phase 1, Phase 2
Record
View on ClinicalTrials.gov ↗